Нови начини в изследванията на Паркинсон: Финансиране на иновативни подходи

Нови начини в изследванията на Паркинсон: Финансиране на иновативни подходи

montag, 22.07.2024

Пробив в изследванията на Паркинсон: възможности чрез епигенетични подходи

д-р rer. Hum. Биол. Björn-Hergen Laabs from the Institute for Medical Biometry and Statistics receives Else Kröner-Fresenius for his research on X-chromosomal dystonia-Parkinson syndrome (XDP). FOTO: Lea Louisa Kronziel/IBMS

Research on X-chromosomal dystonia Parkinson syndrome (XDP), a hereditary illness, receives a new impulse from the work of Dr. Björn-Hergen Laabs an der Universität zu Lübeck. With a generous support of around 300,000 euros from the Else Kröner-Fresenius Foundation, the project aims to expand both the understanding and the possible treatment options of this complex illness.

Изследвания върху факторите на околната среда и генетичната активност

das forschungsprojekt untersucht, wie umweltfaktoren die genaktivität bei xdp-patient*Innen beeinflussen. This is of great importance, since the disease occurs primarily in men in the Philippines and the symptoms, such as involuntary muscle tensions, often reduce the quality of life of those affected considerably. The exact trigger of the symptoms have not yet been fully clarified, which is why Dr. Laabs represents a promising approach.

Нови знания чрез изкуствен интелект

Централен елемент на изследването е използването на изкуствен интелект за анализ на сложни генетични и епигенетични връзки. Методите на AI имат за цел да помогнат за по -доброто прогнозиране на възрастта на засегнатия XDP. Dr. Laabs explains: "I would like to find out whether XDP patients agree faster than healthy people and whether epigenetic profiles can be used to predict the age of illness."

die rolle der epigenetik im krankheitsverständnis

The term epigenetics refers to the changes in genetic activity, which are not due to changes in the DNA sequence itself. В този случай епигенетичните промени могат да окажат решаващо влияние върху това колко трудни или лесно се появяват симптомите на засегнатите. Тези открития биха могли да предложат нова перспектива за бъдещите подходи за терапия.

personal background of Dr. Laabs

dr. Laabs has completed his academic training in medical mathematics and life sciences at the University of Lübeck and specialized in the genetic background of XDP. During his career, he has already received several awards, including the Medical Science Award and the Junior Promotion for his innovative work in the field of mechanical learning.

значение за бъдещето на Parkinsonial Research

This research could not only offer direct advantages for those affected of the XDP, but also show new methods for analysis and possibly to treat other forms of Parkinson's disease. The project represents an important step in research into rare neurological diseases and could provide future -oriented knowledge for science and the medical community.

контакт:

dr. rer. Хъм. Биол. Björn-Hergen Laabs

Institute for Medical Biometry and Statistics

University Zu Lübeck

Тел: 0451 500-50623

e-mail: b.laabs (at) uni-luebeck (dot) de

www.imbs-luebeck.de

- nag